1. Youngquist, B., Saliba, J., Kim, Y., Cutro, T., Lyon, C., JOlivo, J., Ha, N., Colman, R., Vergara, C., Garfein, R., Catanzaro, D., Perez-Then, E., Graviss, E., Mitchell, C., Rodwell, T., Ning, B., Hu, T.* Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay. Science Translational Medicine. 2025, 17, eadp6411. (Cover Story).

2. Ning, B., Chandra, S., Pan, Y., Ha, N., Singh, S., Varela, A., Li, L., Wu, Q., Kay, A., Maphalala, G. P., Adu-Gyamfi, C., Longlax, S., Mandalakas, A. M., Lyon, C., Graviss, E. A., DiNardo, A. R., Hu, T.* Self-Powered Rapid Antigen-Specific T cell Response Assay for Mycobacterium Tuberculosis Infections. Nature Biomedical Engineering. 2025, doi.org/10.1038/s41551-025-01441-5.

3. Saliba, J. G., Zheng, W., Shu, Q., Li, L., Qu, J., Xie, Y., Ying, B., Huang, H., Lyon, C. J., Hu, T.* Enhanced diagnosis of multi-drug-resistant microbes using group association modeling and machine learning. Nature Communications. 2025, 16:2933.

4. Huang, Z., Song, Z., Zeng, J., Liu, X., Fang, M., Chen, Y., Li, D., Huang, H., Fu, L., Xu, P., Ning, B., Lyon, C., Fan, X., Lu, S., Hu, T.* Sensitive pathogen DNA detection by a multi-guide RNA Cas12a assay favoring trans- versus cis-cleavage. Nature Communications. 2025, Accepted.

5. Youngquist, B., Pungan, D., Dai, G., Abdelgallel, Y., Lyon, C., Ning, B., Husain, S., Kolls, J., Hu,T. CRISPR-mediated detection of Pneumocystis transcripts in bronchoalveolar, oropharyngeal, and serum specimens for Pneumocystis pneumonia diagnosis. J. Clinical Investigation. 2025, 135(8):e177241.

6. Wu, J., Dou, Q., Mao, M., Wan, X., Hu, T.*, Zhang, Y.* Single extracellular vesicle imaging via rolling circle amplification–expansion microscopy. Nature Communications. 2025, 16:7498.

7. Li, L., Mao, L., van der Zalm, M. M., Olivo, J., Liu, S., Vergara, C., Palmer, M., Shu, Q., Demers, A., Lyon, C. J., Goussard, P., Schaaf, S., Hesseling, A. C., Nachman, S., Pérez-Then, E., Mitchell, C. D., Ghimenton, E., Hu, T. Blood-based diagnosis of pediatric tuberculosis: a prospective cohort study in South Africa and Dominican Republic. Journal of Infection. 2025, 90(2):106404.

8. Huang, Z., Lyon, C., Hu, T. CRISPR-based assays for low-resource settings. Nature Reviews Bioengineering. 2023, 1:230-231.

9. Zheng, W., LaCourse, S., Song, B., Singh, D. K., Khanna, M., Olivo, J., Stern, J., Escudero, J., Vergara, C., Zhang, F., Li, S., Wang, S., Cranmer, L.M., Huang, Z., Bojanowsk, C.M., Bao, D., Njuguna, I., Xiao, Y., Wamalwa, D. C., Nguyen, D. T., Yang, L., Maleche-Obimbo, E., Nguyen, N., Zhang, L., Phan, H., Fan, J., Ning, B., Li, C., Lyon, C. J., Graviss, E. A., John-Stewart, G., Mitchell, C. D., Ramsay, A. J., Kaushal , D., Liang, R., Pérez-Then, E., Hu, T.* Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples. Nature Biomedical Engineering. 2022, 6, 979-991.

10. Huang, Z., LaCourse, S., Kay A., Stern, J., Escudero, J., Youngquist, B., Zheng, W., Vambe, D., Dlamini, M., Mtetwa, G., Cranmer, L., Njuguna, I., Wamalwa, D., Maleche-Obimbo, E., Catanzaro, D., Lyon, C., John-Stewart, G., DiNardo, A., Mandalakas, A., Ning, B., Hu, T.* CRISPR Detection of Circulating Cell-free M. tuberculosis DNA in Adults and Children, Including Children with HIV. The Lancet Microbe. 2022, 3(7): E482-492.

11. Zheng, W., Shu, Q., Mao L., Lyon, C., Li, C., Hu, T.* Nanopore-based disease diagnosis using pathogen-derived tryptic peptides from serum. Nano Today. 2022, 45:101515.

12. Ning, B., Youngquist, B. M., Li, D. D., Lyon, C. J., Zelazny, A., Maness4, N. J., Tian, D., Hu, T.* Rapid detection of multiple SARS-CoV-2 variants of concern by PAM-targeting Mutations. Cell Reports Method. 2022, 2(2):100173.

13. Ning, B., Huang, Z., Youngquist, B. M, Scott, J. W., Niu, A., Bojanowski, C., M., Zwezdaryk, K. J., Saba, N., S., Fan, J., Yin, X., Cao, J., Lyon, C. J., Li, C., Roy, C. J., Hu, T.* Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma. Nature Nanotechnology. 2021, 16:1039-1044.

14. Ning, B., Yu, T., Zhang, S., Huang, Z., Tian, D., Lin, Z., Niu, A., Golden, N., Hensley, K., Threeton, B., Lyon, C. J., Yin, X., Saba, N., Rappaport, J., Wei, Q., Hu, T.* A smartphone-read ultrasensitive and quantitative saliva test for COVID-19. Science Advances. 2021, 7(2): eabe3703.

15. Huang, Z., Ning, B., Yang, H., Youngquist, B., Niu, A., Lyon, C., Beddingfield, B., Fears, A., Monk, C., Murrell, A., Bilton, S., Linhuber, J., Norton, E., Dietrich, M., Lai, W., Scott, J., Yin, X., Rappaport, J., Robinson, J., Saba, N., Roy, C., Zwezdaryk, K., Zhao, Z., Hu, T.* Sensitive tracking of viral RNA in plasma through all stages of SARS-CoV-2 infection. J. Clinical Investigation. 2021, 131(7):e146031.

16. Hu, T.*, Frieman, M.*, Walfram, J.* Insights from nanomedicine into chloroquine efficacy against COVID-19. Nature Nanotechnology. 2020, 15:247-249.

17. Liu, Y., Fan, J., Xu, T., Ahmadinejad, N., Hess, K., Lin, S., Zhang, J., Liu, X., Liu, X., Ning, B., Liao, Z., Hu, T.* Extracellular Vesicle Tetraspanin-8 Expression Predicts Distant Metastasis in Non-Small Cell Lung Cancer after Concurrent Chemoradiation. Science Advances. 2020, 6:11, eaaz6162.

18. Liu, C., Zhao, Z., Fan, J., Lyon, C. J., Wu, H., Nedelokv, D., Zelazny, A.M., Olivier, K.N., Cazares, L.H., Holland, S.H., Graviss, E. A., Hu, T.* Quantification of Circulating M. tuberculosis Antigens for Rapid Diagnosis and Real-time Treatment Monitoring. Proc. Natl. Acad. Sci. U S A. 2017, 114(15):3969-3974. (Highlighted by New England Journal of Medicine)

19. Liang K., Liu, F., Fan, J., Sun, D., Bernard, D. W., Li, Y., Yokoi, K., Katz, M. H., Koay, E. J., Zhao, Z., Hu, T.* Nanoplasmonic Quantification of Tumor-derived Extracellular Vesicles in Plasma Microsamples for Diagnosis and Treatment Monitoring. Nature Biomedical Engineering. 2017, 1:0021. (Highlighted by Nature Review Gastroenterology & Hepatology)

20. Rodrigues, M., Richards, N., Ning, B., Lyon, C., Hu, T.* Rapid lipid-based normalization of membrane protein expression on extracellular vesicles in complex biological samples. Nano Letters. 2019, 19, 11, 7623-7631 (Cover Story).

代表性论著

1. Biochip Technology

Harwood Academic Publishers 2001 美国

2. Capillary Electrophoresis of Nucleic Acids

Humana Press 2001 美国

3. 生物芯片技术

清华大学出版社 2004 中国

4. 激光指纹术

清华大学出版社 2005 中国

5. The Frontiers of Biochip Technology I

Kluwer Academic Publishers 2005 美国

6. The Frontiers of Biochip Technology II

Kluwer Academic Publishers 2005 美国

7. 生物芯片技术实验室教程

清华大学出版社 2006 中国

8. 生物芯片：生命信息CPU 2006 中国

少年儿童出版社 2006 中国

学术荣誉与奖励

2009 Scholar Development Award, UT Austin

2012 President Award for Transformational Excellence, Houston Methodist Research Institute

2013 Virginia and Ernest Cockrell Junior Faculty Award

2013 Golfer Against Cancer Award

2014 Kostas Cardiovascular Nanomedicine Award

2015 Methodist Cornerstone Award

2015 MSACL Young Investigator Award

2016 John S. Dunn Foundation Award

2016 Translational Research Initiative Award

2018 Arizona Young Investigator Award

2018 NACCCA 2018 Outstanding Research Award

2019 William J. Dorsen Jr. Outstanding Research Award

2020 NACCCA Innovation Award

2021 Tulane Faculty Award in Basic Research

2021 University Innovation Award, Tulane University

2022 Synergy Award, Tulane School of Medicine

2023 University Galaxy Award, Tulane University

2024 Entrepreneurship Award, Tulane University

2025 George Adrouny Memorial Lectureship

2025 Tan Chin Tuan Fellowship (Senior Inbound), Nanyang Technological University in Singapore

2025 The Academy Award for Outstanding Contributions to Clinical Chemistry in a Selected Area of Research, American Association of Clinical Chemistry (AACC)

开设课程

纳米智能材料与医药前沿、纳米生物材料、智能药物载体设计等

其他社会职务

北京市海聚计划战略科学家

北京协和医院名誉教授

美国医学与生物工程学会（AIMBE）会士

美国发明家学院（NAI）院士

国际生物医学工程学院（IABME）院士

《ACS Nano》副主编

授权专利技术

1. WO2011025602A1: Combinatorial multidomain mesoporous chips and a method for fractionation, stabilization, and storage of biomolecules (Licensed to Nanomedicine System Inc., Austin, TX).

2. WO2018151930A1: Compositions and methods of determining a level of infection in a subject (Licensed to Nanopin Technologies Inc., Phoenix, AZ)

3. US20190064178A1: Nanoshell-structured material as co-matrix for peptide characterization in mass spectrometry (Licensed to Nanopin Technologies Inc., Phoenix, AZ)

4. WO2019032824A1: Dark-field microscope apparatus utilizing portable electronic communication device (Licensed to Ares Diagnosis Co., San Jose, CA)

5. PCT/US2021/026436: Monocolnal antibodies and uses thereof (Licensed to Nanopin Technologies Inc., Phoenix, AZ)

6. WO2020252474A2: Detection of antigens (Licensed to Nanopin Technologies Inc., Phoenix, AZ)

7. WO2018126043A1: Nanoplasmonic quantification of tumor-derived extracellular vesicles in plasma microsamples (Licensed to Ares Diagnosis Co., San Jose, CA)

8. Amplifiable nanoparticle enhanced quantitative scattering assay under low magnification dark field microscope (Licensed to Ares Diagnosis Co., San Jose, CA)

9. CRISPR-based assay for detecting SARS-CoV-2 in bodily fluids (Licensed to Nanopin Technologies Inc., Phoenix, AZ)

10. Method of detecting TB in blood (Licensed to Raisecare Technologies Inc., China)

11. Cu Growth Enhanced Plasmonic Assay for Isolation-free Exosome Analysis (Licensed to Raisecare Technologies Inc., China)

12. CRISPR-based Assay for detecting TB in serum (Licensed to Intelligenome LLC., New Orleans, LA)

13. Point-of-care on-Chip IGRA device and method for measuring SARS-CoV-2 Specific T cell activation (Licensed to Intelligenome LLC. New Orleans, LA)

14. Isolation-free, single-tube test for TB diagnosis and multi-drug resistance detection (Licensed to Intelligenome LLC. New Orleans, LA)